SCHEMBL31433673

SCHEMBL31433673

CC(C)(C)OC(=O)N1CCC(CN2CCC(c3ccc4c(C5CCC(=O)NC5=O)n[nH]c4c3F)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 9/20 0.47
▸ CRBN Q96SW2 9/20 0.47
▸ ALOX5AP P20292 2/20 0.41
▸ FEN1 P39748 2/20 0.41
▸ GPR119 Q8TDV5 4/20 0.40
▸ P2RX7 Q99572 1/20 0.36
▸ BACE1 P56817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31433601 0.93 DDB1 (0.52) DDB1CRBNALOX5APFEN1GPR119
SCHEMBL26925042 0.86 DDB1 (0.55) DDB1CRBNALOX5APFEN1GPR119
SCHEMBL30732212 0.86 DDB1 (0.55) DDB1CRBNALOX5APFEN1GPR119
SCHEMBL31433519 0.83 DDB1 (0.37) DDB1CRBN
SCHEMBL26925673 0.80 DDB1 (0.50) DDB1CRBNALOX5APFEN1GPR119
SCHEMBL30732271 0.80 DDB1 (0.50) DDB1CRBNALOX5APFEN1GPR119
SCHEMBL30732069 0.80 DDB1 (0.54) DDB1CRBNALOX5APFEN1P2RX7
SCHEMBL26925408 0.80 DDB1 (0.54) DDB1CRBNALOX5APFEN1P2RX7
SCHEMBL30732000 0.79 DDB1 (0.58) DDB1CRBNALOX5APFEN1GPR119
SCHEMBL26925109 0.79 DDB1 (0.58) DDB1CRBNALOX5APFEN1GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025050016-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-03-06 — — WO disclosed
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