Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15081290 | 0.85 | MAPT (0.48) | OPRK1MAPTALDH1A1CYP2C19GLA | |
| SCHEMBL31433529 | 0.85 | MAPT (0.59) | MAPTALDH1A1GLATDP1MAPK1 | |
| SCHEMBL5593284 | 0.82 | OPRK1 (0.51) | OPRK1MAPTALDH1A1CYP2C19GLA | |
| SCHEMBL4132236 | 0.82 | OPRK1 (0.51) | OPRK1MAPTALDH1A1CYP2C19ALKBH5 | |
| SCHEMBL27978240 | 0.81 | MAPT (0.44) | MAPTALDH1A1CYP2C19GLATDP1 | |
| SCHEMBL2692671 | 0.81 | OPRK1 (0.50) | OPRK1MAPTALDH1A1CYP2C19POLB | |
| SCHEMBL1680354 | 0.81 | OPRK1 (0.50) | OPRK1MAPTALDH1A1CYP2C19GLA | |
| SCHEMBL8326765 | 0.81 | OPRK1 (0.50) | OPRK1MAPTALDH1A1CYP2C19POLB | |
| SCHEMBL30618280 | 0.81 | OPRK1 (0.50) | OPRK1MAPTALDH1A1CYP2C19POLB | |
| SCHEMBL31426614 | 0.81 | OPRK1 (0.50) | OPRK1MAPTALDH1A1CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |