SCHEMBL31433918

SCHEMBL31433918

O=C1CCC(c2n[nH]c3c(F)c(C4CCNCC4)ccc23)C(=O)N1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 20/20 0.41
▸ CRBN Q96SW2 20/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31433519 0.88 DDB1 (0.37) DDB1CRBN
SCHEMBL29321878 0.87 DDB1 (0.46) DDB1CRBN
SCHEMBL25567331 0.82 DDB1 (0.46) DDB1CRBN
SCHEMBL31433601 0.79 DDB1 (0.52) DDB1CRBN
SCHEMBL26924404 0.78 DDB1 (0.60) DDB1CRBN
SCHEMBL25566691 0.78 DDB1 (0.41) DDB1CRBN
Hydrochloric Acid SCHEMBL31433949 0.77 DDB1 (0.59) DDB1CRBN
Hydrochloric Acid SCHEMBL31434024 0.77 DDB1 (0.59) DDB1CRBN
SCHEMBL31323552 0.77 DDB1 (0.48) DDB1CRBN
SCHEMBL25567330 0.76 DDB1 (0.44) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025050016-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-03-06 — — WO disclosed
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