Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15863341 | 0.84 | SMN1; SMN2 (0.41) | MAPTTSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL15863490 | 0.82 | SMN1; SMN2 (0.50) | MAPTTSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL15863337 | 0.82 | SMN1; SMN2 (0.46) | MAPTTSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL15863140 | 0.76 | MAPT (0.34) | MAPTTSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL31434479 | 0.70 | BCHE (0.34) | BCHEALDH1A1KMT2A | |
| SCHEMBL926700 | 0.68 | BCHE (0.50) | MAPTBCHEALDH1A1HPGDMAOB | |
| SCHEMBL15941254 | 0.67 | BACE1 (0.32) | CYP2C19 | |
| SCHEMBL28516262 | 0.67 | MAPK1 (0.40) | TSHRALDH1A1HPGDKDM4EUSP2 | |
| SCHEMBL26108769 | 0.67 | HRH3 (0.48) | MAPTBCHETSHRALDH1A1KMT2A | |
| SCHEMBL15863147 | 0.66 | POLB (0.37) | MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051241-A1 | MACROCYCLIC COMPOUND AND ANTIBODY-DRUG CONJUGATE THEREOF | 劲方医药科技(上海)股份有限公司 | 2025-03-13 | — | — | WO | disclosed |