Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15941254 | 0.85 | BACE1 (0.32) | — | |
| SCHEMBL15863147 | 0.83 | POLB (0.37) | KDM4EALDH1A1 | |
| SCHEMBL4744132 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2TSHRALDH1A1L3MBTL1LMNA | |
| SCHEMBL1143295 | 0.80 | TDP1 (0.49) | ALDH1A1 | |
| SCHEMBL31271525 | 0.80 | BACE1 (0.30) | — | |
| SCHEMBL20363234 | 0.80 | KMT2A (0.41) | MAPK1MTNR1AMTNR1BTSHRUSP2 | |
| SCHEMBL3860740 | 0.80 | MTNR1A (0.34) | KDM4EMTNR1ATSHRL3MBTL1 | |
| SCHEMBL14557540 | 0.79 | ALOX5 (0.32) | — | |
| SCHEMBL15166635 | 0.79 | ZDHHC20 (0.42) | MAPK1TSHRALDH1A1 | |
| SCHEMBL15863341 | 0.78 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2TSHRUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423758-A | Adenosine receptor binding compounds | 尼康治疗公司 | 2021-02-26 | — | — | CN | disclosed |