Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 10/20 | 0.42 |
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23505914 | 0.79 | SMYD3 (0.48) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL31434687 | 0.76 | TBXA2R (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1TBXA2R | |
| SCHEMBL2307275 | 0.74 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL19710589 | 0.74 | SMYD3 (0.58) | — | |
| SCHEMBL21490072 | 0.74 | SMYD3 (0.58) | — | |
| SCHEMBL26987352 | 0.72 | MLLT1 (0.43) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL1811036 | 0.71 | CES1 (0.38) | TSHRALDH1A1 | |
| SCHEMBL2307282 | 0.71 | SMYD3 (0.45) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL19914289 | 0.71 | SMYD3 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1980837 | 0.70 | ALDH1A1 (0.46) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |