SCHEMBL3143517

SCHEMBL3143517

Cc1cc(O)ccc1C1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 2/20 0.40
NUDT1 P36639 1/20 0.39
BACE1 P56817 1/20 0.39
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
PSMB5 P28074 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14115860 0.98 HSP90AB1 (0.40) OPRL1HSP90AB1ESR1ESR2CHRNB2
SCHEMBL16232086 0.94 ESR2 (0.39) ESR1ESR2CHRNB2CHRNA4
SCHEMBL16553931 0.90 CHRNB2 (0.41) OPRL1ESR1ESR2CHRNB2CHRNA4
SCHEMBL9785240 0.85 PTGDR2 (0.41) NUDT1BACE1HSP90AA1HSP90AB1PSMB5
SCHEMBL17699117 0.82 CHRNB2 (0.55) NUDT1BACE1HSP90AA1HSP90AB1ESR1
SCHEMBL2719727 0.81 ESR2 (0.56) ESR1ESR2
SCHEMBL19347098 0.81 HTR2C (0.58) CHRNB2CHRNA4
SCHEMBL31131399 0.81 HTR2C (0.58) CHRNB2CHRNA4
SCHEMBL27628654 0.81 CHRNB2 (0.37) ESR1ESR2CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL25328473 0.80 HTR2C (0.59) CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969272-B2 Hydroxyaromatic functionalized polyalpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US claimed
WO-2014001056-A1 ANTIMICROBIAL COMPOSITION UNILEVER N.V. (NL) 2014-01-03 WO claimed
CN-112601668-B Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2022-07-29 CN disclosed
CN-112601668-A Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2021-04-02 CN disclosed
EP-2137193-B1 SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF SANOFI SA (FR) 2017-08-09 EP disclosed
US-8999631-B2 Primer and pattern forming method for layer including block copolymer TOKYO OHKA KOGYO CO., LTD. (JP) 2015-04-07 US disclosed
CN-104447792-A Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof SANOFI AVENTIS 2015-03-25 CN disclosed
US-8969272-B2 Hydroxyaromatic functionalized polyalpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US disclosed
US-8956810-B2 2015-02-17 US disclosed
US-8642603-B2 Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof SANOFI (FR) 2014-02-04 US disclosed
US-20140030652-A1 PRIMER AND PATTERN FORMING METHOD FOR LAYER INCLUDING BLOCK COPOLYMER RIKEN (JP) 2014-01-30 US disclosed
CN-1031188-C Process for producing hydroxy group-containing alkyl aromatic compound SUMITOMO CHEMICAL CO (JP) 1996-03-06 CN disclosed
EP-0249415-B2 Production of alkylated hydroxy aromatic compounds SUMITOMO CHEMICAL CO (JP) 1995-11-15 EP disclosed
WO-1994028035-A1 POLYMER ALKYLATION OF HYDROXYAROMATIC COMPOUNDS EXXON CHEMICAL PATENTS INC. (US) 1994-12-08 WO disclosed
US-5334775-A Reacting with a terminally unsaturated polymer in the presence of a partially or completely dehydrated heteropoly catalyst; precursors for production of fuel and lubricant additives EXXON CHEMICAL PATENTS INC. (US) 1994-08-02 US disclosed
US-RE34076-E Alkylation catalysis of aromatic alcohol with alkylating agent in presence of heteropoly acid and water SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1992-09-22 US disclosed
US-4912264-A Liquid phase alkylation of a hydroxyl containing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-27 US disclosed
CN-87104109-A Process for producing hydroxy group-containing alkyl aromatic compound 1988-01-20 CN disclosed
EP-0249415-A2 Production of alkylated hydroxy aromatic compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-12-16 EP disclosed
US-3992455-A CHEMICAL INTERMEDIATES FOR INSECTICIDES KOPPERS COMPANY, INC. (US) 1976-11-16 US disclosed