Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20360179 | 0.87 | KARS1 (0.42) | RXRARXRBRXRGKARS1CCNE1 | |
| SCHEMBL20360180 | 0.87 | KARS1 (0.42) | RXRARXRBRXRGKARS1CCNE1 | |
| SCHEMBL17934309 | 0.86 | KARS1 (0.40) | RXRARXRBRXRGKARS1CCNE1 | |
| SCHEMBL17927266 | 0.85 | NR1I2 (0.39) | RXRARXRBRXRGKARS1CCNE1 | |
| SCHEMBL17934310 | 0.85 | NR1I2 (0.39) | RXRARXRBRXRGKARS1CCNE1 | |
| SCHEMBL20366968 | 0.80 | KARS1 (0.40) | RXRARXRBRXRGKARS1CCNE1 | |
| SCHEMBL17927240 | 0.80 | KARS1 (0.38) | RXRARXRBRXRGKARS1CCNE1 | |
| SCHEMBL17927242 | 0.80 | KARS1 (0.38) | RXRARXRBRXRGKARS1CCNE1 | |
| SCHEMBL20359256 | 0.80 | KARS1 (0.42) | RXRARXRBRXRGKARS1CCNE1 | |
| SCHEMBL17934294 | 0.80 | KARS1 (0.42) | RXRARXRBRXRGKARS1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12350312-B2 | Methods for improving adoptive cell therapy | FRED HUTCHINSON CANCER CENTER (US) | 2025-07-08 | — | — | US | disclosed |
| WO-2025090981-A1 | IDENTIFICATION OF THERAPEUTIC TARGETS FOR BIPOLAR DISORDER | THE JOHNS HOPKINS UNIVERSITY (US) | 2025-05-01 | — | — | WO | disclosed |