SCHEMBL31435290

SCHEMBL31435290

CCCc1ccc(CCl)c(SC)c1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
ALOX5 P09917 2/20 0.35
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
ALDH1A1 P00352 2/20 0.31
RAB9A P51151 2/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CA2 P00918 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435294 1.00 CNR1 (0.39) CNR1CNR2ALOX5LPLLIPG
SCHEMBL28803630 0.85 TTR (0.32)
SCHEMBL31435307 0.82 CNR1 (0.43) CNR1CNR2ALOX5LPLLIPG
SCHEMBL11896102 0.74 SKP2 (0.46) CNR1CNR2ALOX5LPLLIPG
SCHEMBL9187867 0.73 CNR1 (0.44) CNR1CNR2ALOX5LPLLIPG
SCHEMBL15897837 0.72 SLC6A4 (0.33) ALDH1A1
SCHEMBL465088 0.71 GABRA1 (0.46) ALOX5ALDH1A1RAB9AMAPK1ATM
SCHEMBL28676403 0.70 CNR1 (0.60) CNR1CNR2ALOX5GABRA1GABRB2
SCHEMBL22826739 0.70 CNR1 (0.41) CNR1CNR2ALOX5LPLLIPG
SCHEMBL7786392 0.69 TTR (0.33) ALDH1A1HPGDSMN1; SMN2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090792-A1 AMIDE PRODRUGS AND USES THEREOF AUTOBAHN THERAPEUTICS, INC. (US) 2025-05-01 WO disclosed