SCHEMBL31435334

SCHEMBL31435334

COC(=O)c1ccc(C2CCC2)c(C(F)(F)F)n1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 3/20 0.43
ALOX5AP P20292 3/20 0.42
FEN1 P39748 3/20 0.42
MAPT P10636 2/20 0.41
CNR2 P34972 6/20 0.38
PLAT P00750 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
HCRTR1 O43613 1/20 0.36
HCRTR2 O43614 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435282 0.96 RBP4 (0.42) RBP4ALOX5APFEN1MAPTCNR2
SCHEMBL31435346 0.94 RBP4 (0.44) RBP4MAPTCNR2PLATCYP1A2
SCHEMBL31435330 0.77 KDM4E (0.41) RBP4CNR2MRGPRX4
SCHEMBL14152715 0.76 MAPT (0.43) ALOX5APFEN1MAPTCNR2CYP1A2
SCHEMBL22977440 0.75 MAPT (0.44) MAPTMRGPRX4HPGD
SCHEMBL27088319 0.74 MAPT (0.45) RBP4MAPTMRGPRX4CYP1A2CYP2C9
SCHEMBL27202830 0.74 NOTUM (0.48) MAPTMRGPRX4CYP1A2CYP2C9
SCHEMBL14152378 0.73 PDK2 (0.41) MAPTCNR2CYP1A2POLBCYP2C9
SCHEMBL14152631 0.73 MAPT (0.44) RBP4ALOX5APFEN1MAPTCNR2
SCHEMBL31435297 0.72 XPO1 (0.44) RBP4MAPTCNR2MRGPRX4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090792-A1 AMIDE PRODRUGS AND USES THEREOF AUTOBAHN THERAPEUTICS, INC. (US) 2025-05-01 WO disclosed