Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502909 | 0.85 | MAPT (0.46) | HASPINMAPTTOP2A | |
| SCHEMBL21957013 | 0.79 | HASPIN (0.44) | HASPINATMMAPTCDC7CDK2 | |
| SCHEMBL10151401 | 0.78 | ATM (0.45) | HASPINATMMAPTNPC1TP53 | |
| SCHEMBL19233649 | 0.77 | CDC7 (0.45) | HASPINATMMAPTNPC1TP53 | |
| SCHEMBL23478504 | 0.74 | ATM (0.41) | HASPINATMMAPTNPC1TP53 | |
| SCHEMBL28861048 | 0.74 | ATM (0.38) | HASPINATMMAPTNPC1TP53 | |
| SCHEMBL23478921 | 0.74 | ATM (0.38) | HASPINATMMAPTNPC1TP53 | |
| SCHEMBL10813893 | 0.73 | BRPF1 (0.54) | ATMSMN1; SMN2POLBTOP2ARAPGEF4 | |
| SCHEMBL23461159 | 0.73 | CYP2A6 (0.40) | HASPINATMMAPTNPC1TP53 | |
| SCHEMBL31751287 | 0.73 | CYP2A6 (0.47) | HASPINATMMAPTNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082069-A1 | COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN | 中国海洋大学 | 2025-04-24 | — | — | WO | disclosed |
| CN-119841843-A | Compound combined with CRBN protein and degradation agent of CRBN protein | 中国海洋大学 | 2025-04-18 | — | — | CN | disclosed |