Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143571 | 1.00 | AKR1B1 (0.46) | AKR1B1GRIK1GPR84PPARGPPARD | |
| SCHEMBL3143579 | 1.00 | AKR1B1 (0.46) | AKR1B1GRIK1GPR84PPARGPPARD | |
| SCHEMBL5271642 | 0.98 | GPR84 (0.48) | AKR1B1GRIK1GPR84PPARGPPARD | |
| SCHEMBL7124107 | 0.98 | GPR84 (0.48) | AKR1B1GRIK1GPR84PPARGPPARD | |
| Bromide SCHEMBL7118666 | 0.94 | GPR84 (0.45) | AKR1B1GRIK1GPR84PPARGPPARD | |
| SCHEMBL395188 | 0.85 | GRIK1 (0.50) | AKR1B1GRIK1GPR84TSHRALDH1A1 | |
| SCHEMBL3151539 | 0.84 | CES1 (0.43) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL3151546 | 0.84 | CES1 (0.43) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL8682392 | 0.82 | AKR1B1 (0.45) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL3146499 | 0.79 | POLB (0.41) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100111888-A1 | Organic Compounds and Compositions Having the Ability to Modulate Fragrance Compositions | GIVAUDAN SA (CH) | 2010-05-06 | — | — | US | claimed |
| EP-2152658-A2 | ORGANIC COMPOUNDS AND COMPOSITIONS HAVING THE ABILITY TO MODULATE FRAGRANCE COMPOSITIONS | Givaudan SA (CH) | 2010-02-17 | — | — | EP | claimed |
| WO-2008116338-A2 | ORGANIC COMPOUNDS AND COMPOSITIONS HAVING THE ABILITY TO MODULATE FRAGRANCE COMPOSITIONS | GIVAUDAN SA (CH) | 2008-10-02 | — | — | WO | claimed |
| US-20100111888-A1 | Organic Compounds and Compositions Having the Ability to Modulate Fragrance Compositions | GIVAUDAN SA (CH) | 2010-05-06 | — | — | US | disclosed |
| EP-2152658-A2 | ORGANIC COMPOUNDS AND COMPOSITIONS HAVING THE ABILITY TO MODULATE FRAGRANCE COMPOSITIONS | Givaudan SA (CH) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008116338-A2 | ORGANIC COMPOUNDS AND COMPOSITIONS HAVING THE ABILITY TO MODULATE FRAGRANCE COMPOSITIONS | GIVAUDAN SA (CH) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100111888-A1 | Organic Compounds and Compositions Having the Ability to Modulate Fragrance Compositions | CYP2A13, CYP1A1, CYP1B1 | AKR1B1 292/4885GRIK1 3456/4885GPR84 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.