SCHEMBL31436044

SCHEMBL31436044

CCCCCCCCCCCCN(CCCCCCCCCCCC)CCCNc1nc(NCCO)nc(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)n1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.67
SLC29A1 Q99808 3/20 0.55
GBA1 P04062 1/20 0.46
DNM2 P50570 9/20 0.43
KCNH3 Q9ULD8 3/20 0.43
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
RECQL P46063 1/20 0.39
MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31436067 1.00 KMT2A (0.67) KMT2ASLC29A1GBA1DNM2KCNH3
SCHEMBL31436130 0.93 KMT2A (0.58) KMT2ASLC29A1GBA1DNM2KCNH3
SCHEMBL31436070 0.93 KMT2A (0.58) KMT2ASLC29A1GBA1DNM2KCNH3
SCHEMBL31436135 0.93 KMT2A (0.56) KMT2ASLC29A1DNM2KCNH3
SCHEMBL31436058 0.93 KMT2A (0.56) KMT2ASLC29A1DNM2KCNH3
SCHEMBL31436099 0.93 KMT2A (0.56) KMT2ASLC29A1DNM2KCNH3
SCHEMBL31436046 0.93 KMT2A (0.56) KMT2ASLC29A1DNM2KCNH3
SCHEMBL31436064 0.92 KMT2A (0.60) KMT2ASLC29A1DNM2KCNH3MEN1
SCHEMBL31436106 0.92 KMT2A (0.60) KMT2ASLC29A1DNM2KCNH3MEN1
SCHEMBL31436082 0.92 KMT2A (0.60) KMT2ASLC29A1DNM2KCNH3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025088570-A1 IONIZABLE LIPIDS AND IONIZABLE LIPID NANOPARTICLES CRISPR THERAPEUTICS AG (CH) 2025-05-01 WO disclosed