SCHEMBL31436082

SCHEMBL31436082

CCCCCCCCCN(CCCCCCCCC)CCCNc1nc(NCCCCO)nc(NCCCN(CCCCCCCCC)CCCCCCCCC)n1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.60
KCNH3 Q9ULD8 4/20 0.48
SLC29A1 Q99808 2/20 0.46
DNM2 P50570 8/20 0.46
LMNA P02545 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31436050 1.00 KMT2A (0.60) KMT2AKCNH3SLC29A1DNM2LMNA
SCHEMBL31436095 1.00 KMT2A (0.60) KMT2AKCNH3SLC29A1DNM2LMNA
SCHEMBL31436106 1.00 KMT2A (0.60) KMT2AKCNH3SLC29A1DNM2LMNA
SCHEMBL31436079 1.00 KMT2A (0.60) KMT2AKCNH3SLC29A1DNM2LMNA
SCHEMBL31436064 1.00 KMT2A (0.60) KMT2AKCNH3SLC29A1DNM2LMNA
SCHEMBL31436070 0.95 KMT2A (0.58) KMT2AKCNH3SLC29A1DNM2
SCHEMBL31436130 0.95 KMT2A (0.58) KMT2AKCNH3SLC29A1DNM2
SCHEMBL31436044 0.92 KMT2A (0.67) KMT2AKCNH3SLC29A1DNM2MEN1
SCHEMBL31436067 0.92 KMT2A (0.67) KMT2AKCNH3SLC29A1DNM2MEN1
SCHEMBL31436046 0.92 KMT2A (0.56) KMT2AKCNH3SLC29A1DNM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025088570-A1 IONIZABLE LIPIDS AND IONIZABLE LIPID NANOPARTICLES CRISPR THERAPEUTICS AG (CH) 2025-05-01 WO disclosed