Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE8B | O95263 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21946826 | 1.00 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM | |
| SCHEMBL31436239 | 0.95 | PDE8B (0.47) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM | |
| SCHEMBL29134838 | 0.91 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM | |
| SCHEMBL15472742 | 0.88 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM | |
| SCHEMBL28239355 | 0.86 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM | |
| SCHEMBL13337700 | 0.86 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM | |
| SCHEMBL894504 | 0.86 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM | |
| SCHEMBL27426143 | 0.86 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM | |
| SCHEMBL144831 | 0.86 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM | |
| SCHEMBL115846 | 0.86 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2PDE8BALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743459-A1 | BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS | D.E. Shaw Research, LLC (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025014922-A1 | BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC (US) | 2025-01-16 | — | — | WO | disclosed |