Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13337700 | 1.00 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL3156957 | 0.94 | PDE8B (0.45) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL27426143 | 0.88 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL894504 | 0.88 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL115846 | 0.88 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL144831 | 0.88 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL25198974 | 0.86 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL21946826 | 0.86 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL7352007 | 0.86 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL31436233 | 0.86 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2NPC1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108391422-A | Pyrrolobenzodiazepine antibody-drug conjugates and methods of use | 豪夫迈·罗氏有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-102427731-A | Hepatitis c virus inhibitors | ENANTA PHARM INC | 2012-04-25 | — | — | CN | disclosed |