SCHEMBL3143645

SCHEMBL3143645

C=C(C(=O)O)c1cccnc1-c1ccccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.49
TDP1 Q9NUW8 1/20 0.49
KDM6B O15054 1/20 0.41
KDM4A O75164 1/20 0.41
KDM5C P41229 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41
KDM3A Q9Y4C1 1/20 0.41
LMNA P02545 3/20 0.41
BLM P54132 2/20 0.41
P4HTM Q9NXG6 2/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
CCR8 P51685 1/20 0.41
METAP1 P53582 1/20 0.41
HIF1A Q16665 1/20 0.41
DOHH Q9BU89 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29693966 0.83 KDM4E (0.71) KDM4ETDP1KDM6BKDM4AKDM5C
SCHEMBL646624 0.83 KDM4E (0.71) KDM4ETDP1KDM6BKDM4AKDM5C
SCHEMBL28561077 0.81 KDM4E (0.69) KDM4ETDP1KDM6BKDM4AKDM5C
SCHEMBL2384672 0.81 KDM4E (0.69) KDM4ETDP1KDM6BKDM4AKDM5C
SCHEMBL28291927 0.81 KDM4E (0.69) KDM4ETDP1KDM6BKDM4AKDM5C
SCHEMBL31214633 0.81 KDM4E (0.69) KDM4ETDP1KDM6BKDM4AKDM5C
SCHEMBL5670751 0.78 KDM4E (0.48) KDM4ETDP1KDM6BKDM4AKDM5C
SCHEMBL14670506 0.78 KDM4E (0.48) KDM4ETDP1KDM6BKDM4AKDM5C
SCHEMBL30423417 0.78 KDM4E (0.48) KDM4ETDP1KDM6BKDM4AKDM5C
SCHEMBL3620548 0.78 GRM5 (0.51) KDM4ETDP1LMNABLMP4HTM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114903028-A Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2022-08-16 CN claimed
CN-114903028-B Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2023-10-17 CN disclosed
CN-114903028-A Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2022-08-16 CN disclosed
EP-2125963-B1 NOBLE RUTHENIUM-TYPE SENSITIZER AND METHOD OF PREPARING THE SAME DONGJIN SEMICHEM CO LTD (KR) 2012-10-31 EP disclosed
US-7645879-B2 Photosensitizer dye NATIONAL CENTRAL UNIVERSITY (TW) 2010-01-12 US disclosed
EP-2125963-A1 NOBLE RUTHENIUM-TYPE SENSITIZER AND METHOD OF PREPARING THE SAME Dongjin Semichem Co., Ltd. (KR) 2009-12-02 EP disclosed
WO-2008102962-A1 NOBLE RUTHENIUM-TYPE SENSITIZER AND METHOD OF PREPARING THE SAME DONGJIN SEMICHEM CO., LTD. (KR) 2008-08-28 WO disclosed