SCHEMBL646624

SCHEMBL646624

O=C(O)c1cccnc1-c1ccccn1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.71
TDP1 Q9NUW8 1/20 0.71
ALDH1A1 P00352 4/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
ALOX15 P16050 2/20 0.53
BLM P54132 2/20 0.53
CYP3A4 P08684 1/20 0.53
MAPT P10636 1/20 0.53
TSHR P16473 1/20 0.53
AGER Q15109 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
LMNA P02545 4/20 0.52
NAPRT Q6XQN6 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
KDM6B O15054 1/20 0.50
KDM4A O75164 1/20 0.50
KDM5C P41229 1/20 0.50
KDM4C Q9H3R0 1/20 0.50
KDM2A Q9Y2K7 1/20 0.50
KDM3A Q9Y4C1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29693966 1.00 KDM4E (0.71) KDM4ETDP1ALDH1A1L3MBTL1ALOX15
SCHEMBL28561077 0.98 KDM4E (0.69) KDM4ETDP1ALDH1A1L3MBTL1ALOX15
SCHEMBL28291927 0.98 KDM4E (0.69) KDM4ETDP1ALDH1A1L3MBTL1ALOX15
SCHEMBL31214633 0.98 KDM4E (0.69) KDM4ETDP1ALDH1A1L3MBTL1ALOX15
SCHEMBL2384672 0.98 KDM4E (0.69) KDM4ETDP1ALDH1A1L3MBTL1ALOX15
Dipyridyl SCHEMBL3954419 0.91 KDM4E (0.75) KDM4ETDP1ALDH1A1L3MBTL1ALOX15
Trifluoroacetic Acid SCHEMBL29693943 0.91 KDM4E (0.59) KDM4ETDP1ALDH1A1L3MBTL1ALOX15
SCHEMBL8195742 0.89 KDM4E (0.61) KDM4ETDP1ALDH1A1L3MBTL1ALOX15
SCHEMBL29260719 0.89 KDM4E (0.61) KDM4ETDP1ALDH1A1L3MBTL1ALOX15
SCHEMBL29267723 0.87 KDM4E (0.54) KDM4ETDP1ALDH1A1L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116626022-A Microsphere composition for chemiluminescence analysis and application thereof 上海索昕生物科技有限公司 2023-08-22 CN claimed
CN-116626021-A Microsphere composition for chemiluminescence analysis and application thereof 上海索昕生物科技有限公司 2023-08-22 CN claimed
CN-116626285-A Homogeneous chemiluminescence analysis method and application thereof 科美博阳诊断技术(上海)有限公司 2023-08-22 CN claimed
CN-116559153-A Homogeneous chemiluminescence detection kit and application thereof 科美博阳诊断技术(上海)有限公司 2023-08-08 CN claimed
CN-116539866-A Homogeneous chemiluminescence analysis method and application thereof 科美博阳诊断技术(上海)有限公司 2023-08-04 CN claimed
CN-116500020-A Chemiluminescence analysis method and application thereof 科美博阳诊断技术(上海)有限公司 2023-07-28 CN claimed
CN-112240930-B Homogeneous chemiluminescence analysis method and application thereof 科美博阳诊断技术(上海)有限公司 2023-07-18 CN claimed
CN-116429757-A Homogeneous chemiluminescence detection kit and application thereof 科美博阳诊断技术(上海)有限公司 2023-07-14 CN claimed
CN-116429758-A Homogeneous chemiluminescence detection kit and application thereof 科美博阳诊断技术(上海)有限公司 2023-07-14 CN claimed
CN-112240936-B Application of donor reagent in diagnosis of myocardial injury of subject 科美博阳诊断技术(上海)有限公司 2023-06-20 CN claimed
US-20090301873-A1 REDOX MEDIATORS OXFORD BIOSENSORS LTD. (GB) 2009-12-10 US claimed
CN-101379033-A Secondary amines ACTELION PHARMACEUTICALS LTD (CH) 2009-03-04 CN claimed
CN-101360755-A Redox mediators OXFORD BIOSENSORS LTD (GB) 2009-02-04 CN claimed
EP-1976856-A2 REDOX MEDIATORS Oxford Biosensors Limited (GB) 2008-10-08 EP claimed
CN-101184733-A Novel piperidine carboxylic acid amide derivatives ACTELION PHARMACEUTICALS LTD (CH) 2008-05-21 CN claimed
WO-2007072018-A2 REDOX MEDIATORS OXFORD BIOSENSORS LTD (GB) 2007-06-28 WO claimed
US-20050159454-A1 Materials and methods for inhibiting fouling of surfaces exposed to aquatic environments KEM WILLIAM R (US) 2005-07-21 US claimed
WO-2005023942-A2 MATERIALS AND METHODS FOR INHIBITING FOULING OF SURFACES EXPOSED TO AQUATIC ENVIRONMENTS UNIVERSITY OF FLORIDA (US) 2005-03-17 WO claimed
US-20040235901-A1 Materials and methods for inhibiting fouling of surfaces exposed to aquatic environments DUKE UNIVERSITY 2004-11-25 US claimed
US-6340599-B1 TERBIUM, DYSPROSIUM, SAMARIUM, OSMIUM, OR RUTHENIUM COMPLEX WITH UNSATURATED OXYARYL COMPOUND DADE BEHRING MARBURG GMBH (DE) 2002-01-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090301873-A1 REDOX MEDIATORS LPO, GPX4, GPX1 KDM4E 3660/4885TDP1 1231/4885ALDH1A1 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.