Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | GLA | P06280 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18786799 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL25613913 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL145353 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL1438722 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL31436516 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL13868306 | 0.75 | TRPV4 (0.43) | KDM4EALDH1A1GAAHPGDATM | |
| SCHEMBL31113834 | 0.75 | TRPV4 (0.43) | KDM4EALDH1A1GAAHPGDATM | |
| SCHEMBL13550103 | 0.74 | AR (0.35) | ARHTT | |
| SCHEMBL80564 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL13550078 | 0.74 | KDM1A (0.34) | ARHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743079-A2 | APOL1 INHIBITORS AND METHODS OF USE THEREOF | Maze Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015106-A2 | APOL1 INHIBITORS AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |