SCHEMBL31436622

SCHEMBL31436622

CC(C)Nc1cc(Cl)ncc1C(=O)NC1CC1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26598605 1.00 IRAK4 (0.61) IRAK4
SCHEMBL18882610 0.95 IRAK4 (0.64) IRAK4
SCHEMBL21379161 0.95 IRAK4 (0.57) IRAK4
SCHEMBL21765615 0.95 IRAK4 (0.57) IRAK4
SCHEMBL21379077 0.94 IRAK4 (0.57) IRAK4
SCHEMBL21379047 0.94 IRAK4 (0.57) IRAK4
SCHEMBL16873243 0.93 IRAK4 (0.56) IRAK4
SCHEMBL15714717 0.93 IRAK4 (0.56) IRAK4
SCHEMBL21379215 0.92 IRAK4 (0.63) IRAK4
SCHEMBL16873434 0.92 IRAK4 (0.66) IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119585250-A KIT inhibitors 蓝图药品公司 2025-03-07 CN disclosed