Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.45 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 8/20 | 0.39 |
| ▸ | JAK2 | O60674 | 7/20 | 0.39 |
| ▸ | JAK1 | P23458 | 7/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26598641 | 1.00 | IRAK4 (0.45) | IRAK4NNMTNUDT1LRRK2TYK2 | |
| SCHEMBL31678676 | 0.91 | IRAK4 (0.39) | IRAK4NNMTNUDT1LRRK2TYK2 | |
| SCHEMBL31678695 | 0.91 | IRAK4 (0.39) | IRAK4NNMTNUDT1LRRK2TYK2 | |
| SCHEMBL25074121 | 0.87 | NNMT (0.43) | IRAK4NNMTKDM4EALDH1A1GLA | |
| SCHEMBL30043246 | 0.87 | NNMT (0.43) | IRAK4NNMTKDM4EALDH1A1GLA | |
| SCHEMBL6223582 | 0.84 | KDM4C (0.46) | NNMTLRRK2KDM4EALDH1A1GLA | |
| SCHEMBL31436671 | 0.84 | IRAK4 (0.39) | IRAK4NNMTNUDT1TYK2JAK2 | |
| SCHEMBL31678698 | 0.84 | LRRK2 (0.39) | IRAK4NNMTLRRK2JAK2JAK1 | |
| SCHEMBL31436577 | 0.84 | IRAK4 (0.55) | IRAK4 | |
| SCHEMBL26598686 | 0.84 | IRAK4 (0.39) | IRAK4NNMTNUDT1TYK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585250-A | KIT inhibitors | 蓝图药品公司 | 2025-03-07 | — | — | CN | disclosed |