Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 10/20 | 0.45 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24571655 | 1.00 | RET (0.45) | RETARGPR183NR1H2NR1H3 | |
| SCHEMBL21877282 | 0.91 | EGLN2 (0.48) | RETARNR1H2NR1H3GPR119 | |
| SCHEMBL20235026 | 0.88 | MAPT (0.49) | RETNR1H2NR1H3GPR119EGLN2 | |
| SCHEMBL30612711 | 0.88 | MAPT (0.49) | RETNR1H2NR1H3GPR119EGLN2 | |
| SCHEMBL31155546 | 0.84 | HSD17B10 (0.47) | RETARNR1H2NR1H3GPR119 | |
| SCHEMBL30906240 | 0.84 | MAPK3 (0.49) | RETNR1H2NR1H3GPR119EGLN2 | |
| SCHEMBL25212034 | 0.83 | CYP11B2 (0.43) | GPR183NR1H2NR1H3GPR119CYP11B2 | |
| SCHEMBL30423051 | 0.83 | CYP11B2 (0.41) | GPR183NR1H2NR1H3GPR119CYP11B2 | |
| SCHEMBL25202645 | 0.83 | CYP11B2 (0.41) | GPR183NR1H2NR1H3GPR119CYP11B2 | |
| SCHEMBL30423454 | 0.83 | CYP11B2 (0.43) | GPR183NR1H2NR1H3GPR119CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152967-A | Bifunctional compounds containing 2, 5-substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |