SCHEMBL31437189

SCHEMBL31437189

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)O)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPK8 P45983 1/20 0.54
▸ MAPK9 P45984 1/20 0.54
▸ MAPK10 P53779 1/20 0.54
▸ KDM1A O60341 3/20 0.52
▸ KEAP1 Q14145 1/20 0.49
▸ MAOB P27338 1/20 0.49
▸ KDM5A P29375 1/20 0.49
▸ KDM1B Q8NB78 1/20 0.49
▸ EPHA2 P29317 3/20 0.49
▸ TFPI P10646 3/20 0.47
▸ RAMP3 O60896 6/20 0.46
▸ CALCR P30988 6/20 0.46
▸ NPY1R P25929 2/20 0.45
▸ NPY2R P49146 2/20 0.45
▸ NPY4R P50391 2/20 0.45
▸ NPY5R Q15761 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31467754 0.91 KDM1A (0.59) MAPK8MAPK9MAPK10KDM1AMAOB
SCHEMBL31467773 0.90 RAMP3 (0.51) EPHA2TFPIRAMP3CALCRNPY1R
SCHEMBL31437188 0.90 KEAP1 (0.50) MAPK8MAPK9MAPK10KDM1AKEAP1
SCHEMBL31467763 0.89 EPHA2 (0.48) KEAP1EPHA2TFPIRAMP3CALCR
SCHEMBL31437159 0.87 CXCR4 (0.54) EPHA2TFPINPY1RNPY2RNPY4R
SCHEMBL30978864 0.87 MAPK8 (0.49) MAPK8MAPK9MAPK10KDM1AKEAP1
SCHEMBL30311307 0.85 KDM1A (0.60) MAPK8MAPK9MAPK10KDM1AKEAP1
SCHEMBL30311519 0.85 MAPK8 (0.60) MAPK8MAPK9MAPK10KDM1AMAOB
SCHEMBL30432784 0.85 KDM1A (0.58) MAPK8MAPK9MAPK10KDM1AMAOB
Acetic Acid SCHEMBL30408714 0.84 KDM1A (0.59) MAPK8MAPK9MAPK10KDM1AKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025037992-A1 NEW PEPTIDES AND USE THEREOF MAJEWSKI FILIP (PL) 2025-02-20 — — WO disclosed
WO-2025037993-A1 DOSAGE FORM FOR PEPTIDE AGENTS MAJEWSKI FILIP (PL) 2025-02-20 — — WO disclosed
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