SCHEMBL31437487

SCHEMBL31437487

NCc1c(Br)cccc1OC(F)F

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
DPP4 P27487 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
KCNH2 Q12809 1/20 0.34
DRD1 P21728 1/20 0.32
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.30
MBOAT4 Q96T53 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16797141 0.84 KMT2A (0.39) KMT2AMEN1HTTSLC6A2SLC6A4
SCHEMBL16797206 0.82 KMT2A (0.41) KMT2AMEN1HTTSLC6A2SLC6A4
SCHEMBL16797182 0.80 SLC6A2 (0.46) KMT2AHTTDPP4SLC6A2SLC6A4
SCHEMBL15540477 0.79 DPP4 (0.57) KMT2AMEN1HTTDPP4SLC6A2
SCHEMBL16756473 0.77 MEN1 (0.38) KMT2AMEN1HTTSLC6A2SLC6A4
SCHEMBL27797008 0.76 HTR2A (0.42) KMT2AMEN1DPP4ALDH1A1
SCHEMBL264299 0.74 DRD1 (0.42) KMT2AMEN1HTTDRD1ALDH1A1
SCHEMBL29819809 0.74 DRD1 (0.42) KMT2AMEN1HTTDRD1ALDH1A1
SCHEMBL28879840 0.73 TAAR1 (0.42) DPP4SLC6A2SLC6A4ALDH1A1
SCHEMBL2031163 0.73 HTT (0.41) KMT2AMEN1HTTSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125389-A1 MEMBRANE-ASSOCIATED TYROSINE AND THREONINE KINASE INHIBITOR AND USE THEREOF HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO LTD (CN) 2026-05-07 US disclosed
CN-119894902-A Membrane associated tyrosine and threonine kinase inhibitors and uses thereof 海南先声再明医药股份有限公司 2025-04-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125389-A1 MEMBRANE-ASSOCIATED TYROSINE AND THREONINE KINASE INHIBITOR AND USE THEREOF PKMYT1, PKN1, ROS1 KMT2A 930/4885MEN1 1426/4885HTT 3706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.