Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819809 | 1.00 | DRD1 (0.42) | DRD1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL22823665 | 0.82 | HTR1A (0.46) | HTR1AADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL1400223 | 0.82 | HTR1A (0.39) | HTR1AADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL4654255 | 0.82 | DRD1 (0.48) | DRD1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29867899 | 0.80 | HTT (0.41) | DRD1KMT2AHTTMEN1SMN1; SMN2 | |
| SCHEMBL28310793 | 0.80 | IDO1 (0.39) | HTR1AADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL2031163 | 0.80 | HTT (0.41) | DRD1KMT2AHTTMEN1SMN1; SMN2 | |
| SCHEMBL25435045 | 0.79 | ALDH1A1 (0.42) | DRD1KMT2AHTTMEN1SMN1; SMN2 | |
| SCHEMBL8984707 | 0.79 | HTR1A (0.37) | HTR1AADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL31399767 | 0.79 | KMT2A (0.40) | DRD1KMT2AHTTMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083602-A | A kind of synthetic method of phenformin pharmaceutical intermediate β phenethylamine | 成都切斯特科技有限公司 | 2016-11-09 | — | — | CN | claimed |
| US-12630566-B2 | KRas G12D inhibitors | Mirati Therapeutics, Inc. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260109715-A1 | IMIDAZOPYRIDINE DERIVATIVES WITH BICYCLIC STRUCTURE | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2026-04-23 | — | — | US | disclosed |
| US-20260055062-A1 | HETEROCYCLIC INHIBITORS OF MCT4 | Vettore, LLC | 2026-02-26 | — | — | US | disclosed |
| US-20260049074-A1 | THIADIAZOLYL DERIVATIVES | IDEAYA BIOSCIENCES, INC. (US) | 2026-02-19 | — | — | US | disclosed |
| US-12509454-B2 | Thiadiazolyl derivatives | IDEAYA BIOSCIENCES, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-12492171-B2 | Heterocyclic inhibitors of MCT4 | Vettore, LLC (US) | 2025-12-09 | — | — | US | disclosed |
| US-20250325552-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| EP-4600246-A1 | IMIDAZOPYRIDINE DERIVATIVES WITH BICYCLIC STRUCTURE | Public University Corporation Yokohama City University (JP) | 2025-08-13 | — | — | EP | disclosed |
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2003018535-A2 | NOVEL AMINOBENZOEPHENONES | LEO PHARMA A/S (DK) | 2003-03-06 | — | — | WO | disclosed |
| EP-0393513-B1 | Preparation of a difluorohalomethoxybenzene | MITSUI TOATSU CHEMICALS (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5105021-A | Reacting metal phenolate with (di)bromo(chloro)difluoromethane in presence of promoter | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0393513-A1 | Preparation of a difluorohalomethoxybenzene | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-24 | — | — | EP | disclosed |
| EP-0147298-B1 | SULFONYLATION PROCESS | RHONE-POULENC CHIMIE (FR) | 1989-04-26 | — | — | EP | disclosed |
| US-4618726-A | DEACTIVATED BENZENE COMPOUND WITH CARBONYL HALIDE IN LIQUID HYDROFLUORIC ACID AND BORON TRIFLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1986-10-21 | — | — | US | disclosed |
| EP-0147298-A2 | Sulfonylation process | RHONE-POULENC CHIMIE (FR) | 1985-07-03 | — | — | EP | disclosed |
| EP-0052558-B1 | AROMATIC BROMOPOLYFLUOROALKYL ETHERS, AND PROCESS FOR THEIR PREPARATION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-10-03 | — | — | EP | disclosed |
| US-4377711-A | Novel aromatic bromopolyfluoroalkyl ethers and method for the preparation thereof | RHONE-POULENC INDUSTRIES (FR) | 1983-03-22 | — | — | US | disclosed |
| EP-0052558-A1 | Aromatic bromopolyfluoroalkyl ethers, and process for their preparation | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1982-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12492171-B2 | Heterocyclic inhibitors of MCT4 | SLC16A3, SLC16A1, MCTS1 | DRD1 4758/4885HTR1A 2313/4885ADRA2A 4616/4885 |
| US-20260049074-A1 | THIADIAZOLYL DERIVATIVES | POLH, POLM, POLD1 | DRD1 2052/4885HTR1A 2674/4885ADRA2A 838/4885 |
| US-20250325552-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | POLQ, POLK, POLH | DRD1 4199/4885HTR1A 4304/4885ADRA2A 3026/4885 |
| US-12630566-B2 | KRas G12D inhibitors | KRAS, NRAS, HRAS | DRD1 3863/4885HTR1A 4856/4885ADRA2A 4569/4885 |
| US-20260109715-A1 | IMIDAZOPYRIDINE DERIVATIVES WITH BICYCLIC STRUCTURE | SMG1, RACK1, TIA1 | DRD1 2544/4885HTR1A 3198/4885ADRA2A 3086/4885 |
| US-12509454-B2 | Thiadiazolyl derivatives | POLD1, POLQ, DNA2 | DRD1 769/4885HTR1A 2705/4885ADRA2A 1621/4885 |
| US-20260055062-A1 | HETEROCYCLIC INHIBITORS OF MCT4 | SLC16A1, SLC16A3, SLC16A7 | DRD1 1700/4885HTR1A 627/4885ADRA2A 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.