⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720188 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27912104 | 0.97 | — | — | |
| Formaldehyde SCHEMBL29175656 | 0.93 | SIRT3 (0.44) | — | |
| Cyanide SCHEMBL27862175 | 0.93 | SIRT3 (0.39) | — | |
| Oxirane SCHEMBL29170802 | 0.89 | SIRT3 (0.37) | — | |
| SCHEMBL793800 | 0.83 | — | — | |
| SCHEMBL550773 | 0.79 | — | — | |
| SCHEMBL29741232 | 0.79 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27884564 | 0.78 | CA12 (0.36) | — | |
| Hydrochloric Acid SCHEMBL25411609 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124455-B | Preparation method of tofacitinib intermediate | 南通常佑药业科技有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-114644636-B | Method for preparing tofacitinib key intermediate | 江苏恒沛药物科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-115124455-A | Preparation method of tofacitinib intermediate | 南通常佑药业科技有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-114644636-A | Method for preparing tofacitinib key intermediate | 江苏恒沛药物科技有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-109851551-B | Method for synthesizing 3-bromoisonicotinic acid intermediate | 大连金点生物科技有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-110746348-A | Preparation method of 4-methyl-3-bromopyridine | 常州传侑环保科技有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-109761891-A | A kind of preparation method of 4- methyl -3- bromopyridine | 丹阳市宁大卫防检测技术有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-107698583-A | A kind of preparation method of imidazopyridine derivatives | 湖南华腾制药有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-106243022-A | A kind of preparation method of nevirapine intermediate | 湖南大学 | 2016-12-21 | — | — | CN | claimed |
| CN-204776529-U | 4 - methyl - 3 - bromopyridine deposits jar | HONG SHUAIJIN | 2015-11-18 | — | — | CN | claimed |
| CN-204776926-U | 4 - methyl - 3 - bromopyridine saves jar | HONG SHUAIJIN | 2015-11-18 | — | — | CN | claimed |
| CN-204768480-U | 4 - methyl - chemical tank for 3 - bromopyridine | HUANG RONGHUI | 2015-11-18 | — | — | CN | claimed |
| CN-204776927-U | 4 - methyl - 3 - bromopyridine preserves jar | HONG SHUAIJIN | 2015-11-18 | — | — | CN | claimed |
| CN-204768341-U | 4 - methyl - 3 - bromopyridine agitator | HONG SHUAIJIN | 2015-11-18 | — | — | CN | claimed |
| CN-104945314-A | Method for preparing 3-bromo-4-methylpyridine | HONG SHUAIJIN | 2015-09-30 | — | — | CN | claimed |
| CN-117024411-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-4735430-A1 | MALT1 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2026-05-06 | — | — | EP | disclosed |
| US-4536344-A | USING A PHOSPINE OR PHOSPHITE | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-20 | — | — | US | disclosed |
| EP-0109606-A1 | Process for the formylation of aryl halides | BAYER AG (DE) | 1984-05-30 | — | — | EP | disclosed |
| US-4022897-A | 4H-PYRIDO(1,2-A) PYRIMIDIN-4-ONE DERIVATIVES | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | disclosed |