Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 1/20 | 0.58 |
| ▸ | PTPRE | P23469 | 1/20 | 0.58 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31438265 | 0.83 | PTPRC (0.47) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL5188581 | 0.81 | PTPRC (0.55) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL4084024 | 0.81 | PTPRC (0.55) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL31438295 | 0.80 | PTPRC (0.44) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL1397792 | 0.80 | PTPRC (0.44) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL2285281 | 0.77 | KEAP1 (0.58) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL987855 | 0.75 | PTPRC (0.43) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL26978265 | 0.75 | AHR (0.52) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL486824 | 0.75 | DPP4 (0.71) | DPP4KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL6318130 | 0.74 | PTPN1 (1.00) | PTPRCPTPN2PTPN1PTPRBPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585257-A | Novel 7-substituted indole sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-03-07 | — | — | CN | disclosed |