Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25190538 | 1.00 | PTPN1 (0.39) | PTPN1CCR1HPGDSGSK3B | |
| SCHEMBL31438572 | 0.82 | PTPN1 (0.36) | PTPN1HPGDSGSK3B | |
| SCHEMBL21566182 | 0.79 | PTPN1 (0.41) | PTPN1HPGDSGSK3B | |
| Bromide SCHEMBL16753263 | 0.76 | GABRP (0.40) | PTPN1HPGDSGSK3B | |
| SCHEMBL31438509 | 0.73 | APP (0.37) | PTPN1HPGDSGSK3B | |
| SCHEMBL25188090 | 0.73 | APP (0.37) | PTPN1HPGDSGSK3B | |
| SCHEMBL19434412 | 0.73 | PTPN1 (0.37) | PTPN1HPGDSGSK3B | |
| SCHEMBL28904627 | 0.71 | PTPN1 (0.35) | PTPN1HPGDSGSK3B | |
| SCHEMBL18153003 | 0.71 | MAPK8 (0.42) | PTPN1HPGDS | |
| SCHEMBL22045433 | 0.70 | PARP1 (0.40) | PTPN1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134035-B | 3- (1H-imidazol-2-yl) -2,3,8 a-tetrahydroindol-5 (1H) -one derivatives useful as factor XIA inhibitors | 詹森药业有限公司 | 2025-03-11 | — | — | CN | disclosed |