SCHEMBL31438693

SCHEMBL31438693

COC(=O)NNC(=O)c1cc(Br)cc(Br)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.41
ALDH1A1 P00352 1/20 0.35
MALT1 Q9UDY8 9/20 0.34
LRRK2 Q5S007 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
RBP4 P02753 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121385 1.00 DHODH (0.41) DHODHALDH1A1MALT1LRRK2MEN1
SCHEMBL13073075 0.93 DHODH (0.41) DHODHALDH1A1MALT1MEN1KMT2A
SCHEMBL13072911 0.92 DHODH (0.40) DHODHALDH1A1MALT1MEN1KMT2A
SCHEMBL13318579 0.92 DHODH (0.40) DHODHALDH1A1MALT1MEN1KMT2A
SCHEMBL12911637 0.91 DHODH (0.40) DHODHALDH1A1MALT1LRRK2MEN1
SCHEMBL13072526 0.91 DHODH (0.35) DHODHALDH1A1MALT1LRRK2MEN1
SCHEMBL12559867 0.90 DHODH (0.45) DHODHALDH1A1MALT1MEN1KMT2A
SCHEMBL15525072 0.90 DHODH (0.41) DHODHMALT1LRRK2MEN1KMT2A
SCHEMBL536164 0.90 DHODH (0.42) DHODHALDH1A1MALT1MEN1KMT2A
SCHEMBL13072488 0.89 DHODH (0.37) DHODHALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025056008-A1 PYRIPYROPENE DERIVATIVE, AND COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2025-03-20 WO disclosed
CN-119613426-A Pyripyropene derivative, composition and application thereof 青岛清原化合物有限公司 2025-03-14 CN disclosed