Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25785378 | 0.78 | AXL (0.36) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL25786093 | 0.77 | DRD2 (0.53) | ALDH1A1LMNAHSD17B10HPGDDRD2 | |
| SCHEMBL1511313 | 0.74 | CYP4F2 (0.69) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL31439901 | 0.73 | DRD2 (0.35) | TBXAS1DRD2DRD4DRD3 | |
| SCHEMBL31440107 | 0.72 | NPC1 (0.45) | ALDH1A1HSD17B10HPGDDRD2DRD4 | |
| SCHEMBL18371229 | 0.72 | CYP4F2 (0.60) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL31440114 | 0.71 | AXL (0.36) | TBXAS1DRD2DRD4DRD3 | |
| SCHEMBL34471549 | 0.70 | CYP4F2 (0.57) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL17540563 | 0.70 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL4033051 | 0.70 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747260-A1 | MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025021666-A1 | MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-30 | — | — | WO | disclosed |