Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927300 | 0.86 | EPAS1 (0.46) | EPAS1NR3C1CARM1PRMT6PKM | |
| SCHEMBL15068243 | 0.83 | EPAS1 (0.52) | EPAS1NR3C1PKMMAPTMEN1 | |
| SCHEMBL30154414 | 0.80 | GABRA1 (0.36) | EPAS1NR3C1CARM1PRMT6GABRA1 | |
| SCHEMBL30444289 | 0.80 | EPAS1 (0.52) | EPAS1NR3C1CARM1PRMT6PKM | |
| SCHEMBL15067971 | 0.80 | EPAS1 (0.52) | EPAS1NR3C1CARM1PRMT6PKM | |
| SCHEMBL20384450 | 0.79 | EPAS1 (0.51) | EPAS1NR3C1PKMMAPTMEN1 | |
| SCHEMBL15068139 | 0.78 | EPAS1 (0.48) | EPAS1NR3C1CARM1PRMT6PKM | |
| SCHEMBL5793915 | 0.76 | GABRA1 (0.52) | NR3C1GABRA1GABRB2MAPTL3MBTL1 | |
| SCHEMBL15067636 | 0.76 | EPAS1 (0.55) | EPAS1NR3C1 | |
| SCHEMBL30443821 | 0.76 | EPAS1 (0.55) | EPAS1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116135858-B | Furanopyridone compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2025-04-01 | — | — | CN | disclosed |