Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.80 |
| ▸ | PGR | P06401 | 4/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.80 |
| ▸ | TNF | P01375 | 1/20 | 0.80 |
| ▸ | IL6 | P05231 | 1/20 | 0.80 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.80 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.80 |
| ▸ | AR | P10275 | 1/20 | 0.80 |
| ▸ | GLUL | P15104 | 1/20 | 0.80 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.80 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deprodone SCHEMBL11584541 | 1.00 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Deprodone SCHEMBL121194 | 1.00 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Deprodone SCHEMBL12738232 | 1.00 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Loteprednol SCHEMBL12396678 | 0.92 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Loteprednol SCHEMBL5095876 | 0.92 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Loteprednol SCHEMBL23974878 | 0.92 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Loteprednol SCHEMBL1685771 | 0.92 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Loteprednol SCHEMBL15803210 | 0.92 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Loteprednol SCHEMBL12738241 | 0.92 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Loteprednol SCHEMBL1626518 | 0.92 | NR3C1 (0.80) | NR3C1HIF1APGRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119614528-A | Hydroxy steroid dehydrogenase mutant and application thereof in preparation of steroid drugs | 台州仙琚药业有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119614528-A | Hydroxy steroid dehydrogenase mutant and application thereof in preparation of steroid drugs | 台州仙琚药业有限公司 | 2025-03-14 | — | — | CN | disclosed |