Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010104 | 0.94 | NAAA (0.46) | NAAAMAPTPARP1SMOHTT | |
| SCHEMBL2009491 | 0.93 | NAAA (0.46) | NAAACHRM4PARP1SMO | |
| SCHEMBL2007402 | 0.89 | CPS1 (0.46) | NAAA | |
| SCHEMBL2002581 | 0.86 | SMO (0.51) | NAAAMAPTCYP2C9CYP2C19SMO | |
| SCHEMBL2014337 | 0.86 | NAAA (0.50) | NAAASMO | |
| SCHEMBL2010642 | 0.85 | NAAA (0.49) | NAAASMO | |
| SCHEMBL2008063 | 0.85 | NAAA (0.49) | NAAASMO | |
| SCHEMBL2004262 | 0.85 | SMO (0.53) | NAAASMO | |
| SCHEMBL2012545 | 0.84 | NAAA (0.49) | NAAAMAPTSMO | |
| SCHEMBL2002553 | 0.84 | NAAA (0.48) | NAAAMAPTSMOHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981504-B1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | REMYND NV (BE) | 2010-07-21 | — | — | EP | claimed |