SCHEMBL3144343

SCHEMBL3144343

COCCn1c(S)nc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.64
RAB9A P51151 5/20 0.58
KDM4E B2RXH2 4/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
NPC1 O15118 4/20 0.58
ALDH1A1 P00352 3/20 0.58
GLA P06280 1/20 0.58
GAA P10253 1/20 0.58
TSHR P16473 3/20 0.56
CASR P41180 1/20 0.56
TP53 P04637 1/20 0.54
KMT2A Q03164 1/20 0.54
RECQL P46063 1/20 0.54
HSD17B10 Q99714 1/20 0.54
LMNA P02545 2/20 0.52
PKM P14618 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
AR P10275 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7854878 0.84 KDM4E (0.66) RAB9AKDM4ESMN1; SMN2ALDH1A1TSHR
SCHEMBL14557079 0.84 CXCR4 (0.52) SMN1; SMN2TP53KMT2ARECQLLMNA
SCHEMBL1104424 0.83 KDM4E (0.62) HPGDRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL5009001 0.82 HPGD (0.70) HPGDRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL3140332 0.81 POLB (0.65) HPGDRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL15595665 0.81 POLB (0.69) HPGDRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL18584288 0.81 HPGD (0.64) HPGDRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL18046824 0.81 HPGD (0.64) HPGDRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL14557060 0.80 CXCR4 (0.61) SMN1; SMN2ALDH1A1GAATSHRTP53
SCHEMBL5379370 0.79 TSHR (0.65) HPGDRAB9AKDM4ESMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246699-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2090933-A1 Lithographic printing plate precursor and printing method FUJIFILM Corporation (JP) 2009-08-19 EP disclosed
US-20090197205-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed
EP-2006738-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2008-12-24 EP disclosed