SCHEMBL1104424

SCHEMBL1104424

COCn1c(S)nc2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.62
HSD17B10 Q99714 3/20 0.62
RAB9A P51151 6/20 0.56
NPC1 O15118 5/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
ALDH1A1 P00352 5/20 0.56
TP53 P04637 4/20 0.56
MAPT P10636 2/20 0.56
LMNA P02545 4/20 0.52
TSHR P16473 3/20 0.52
HPGD P15428 2/20 0.52
MAPK1 P28482 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.47
HTT P42858 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
GLA P06280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3144343 0.83 HPGD (0.64) KDM4EHSD17B10RAB9ANPC1SMN1; SMN2
SCHEMBL2202012 0.80 HTT (0.62) KDM4EHSD17B10RAB9ANPC1SMN1; SMN2
SCHEMBL14557079 0.80 CXCR4 (0.52) SMN1; SMN2TP53MAPTLMNAHTT
SCHEMBL23421979 0.79 KDM4E (0.62) KDM4EHSD17B10RAB9ANPC1SMN1; SMN2
SCHEMBL18640757 0.79 CYP1A2 (0.67) KDM4EHSD17B10RAB9ANPC1SMN1; SMN2
SCHEMBL12730935 0.78 KMT2A (0.48) KDM4EHSD17B10RAB9ANPC1SMN1; SMN2
SCHEMBL3140332 0.77 POLB (0.65) KDM4EHSD17B10RAB9ANPC1SMN1; SMN2
SCHEMBL31189925 0.77 SMN1; SMN2 (0.65) KDM4EHSD17B10RAB9ANPC1SMN1; SMN2
SCHEMBL31189923 0.77 RAB9A (0.65) KDM4EHSD17B10RAB9ANPC1SMN1; SMN2
SCHEMBL14112988 0.77 MEN1 (0.49) RAB9ASMN1; SMN2ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-20110168044-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
US-7923197-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
US-20110020751-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRODUCTION PROCESS OF LITHOGRAPHIC PRINTING PLATE USING THE PRECURSOR FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110017084-A1 IMMERSION TYPE AUTOMATIC DEVELOPING APPARATUS FOR LITHOGRAPHIC PRINTING PLATE AND AUTOMATIC DEVELOPING METHOD FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-7811743-B2 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-20080261153-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-20080241739-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080160451-A1 METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20070287098-A1 MEHTOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2007-12-13 US disclosed
US-20070231745-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed