Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443697 | 0.90 | SCN9A (0.41) | SCN9ANR1H2NR1H3RORCF10 | |
| SCHEMBL31443523 | 0.89 | SCN9A (0.39) | SCN9ANR1H2NR1H3RORCCYP1A2 | |
| SCHEMBL31443472 | 0.89 | SCN9A (0.39) | SCN9ANR1H2NR1H3RORCCYP1A2 | |
| SCHEMBL31443518 | 0.86 | MAPK1 (0.36) | SCN9ANR1H2NR1H3MAPK1NR1H4 | |
| SCHEMBL31443553 | 0.86 | NR1H2 (0.32) | SCN9ANR1H2NR1H3RORCF10 | |
| SCHEMBL31443496 | 0.86 | MAPK1 (0.36) | SCN9ANR1H2NR1H3MAPK1NR1H4 | |
| SCHEMBL31443473 | 0.85 | MEN1 (0.35) | SCN9ANR1H2NR1H3MAPK1NR1H4 | |
| SCHEMBL31444591 | 0.85 | MEN1 (0.35) | SCN9ANR1H2NR1H3MAPK1NR1H4 | |
| SCHEMBL31443607 | 0.85 | SCN9A (0.34) | SCN9ANR1H2NR1H3MAPK1NR1H4 | |
| SCHEMBL31443447 | 0.85 | NR1H2 (0.32) | SCN9ANR1H2NR1H3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | claimed |
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |