Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP4 | P49662 | 1/20 | 0.37 |
| ▸ | CASP5 | P51878 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 7/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443490 | 1.00 | CASP1 (0.37) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL31443453 | 0.99 | CASP1 (0.37) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL31443562 | 0.99 | CASP1 (0.37) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL31443633 | 0.97 | CASP1 (0.39) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL31443624 | 0.97 | CASP1 (0.39) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL31443656 | 0.90 | CNR2 (0.36) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL31443573 | 0.89 | KMT2A (0.38) | CCR1PDE5ASMYD3CNR2ALDH1A1 | |
| SCHEMBL31443486 | 0.87 | USP30 (0.35) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL31443852 | 0.87 | USP30 (0.35) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL31443863 | 0.87 | SCN9A (0.35) | CASP1CASP4CASP5CASP7CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | claimed |
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |