SCHEMBL31443772

SCHEMBL31443772

O=C(O)CN1CCC(c2ccc(OC3CCC(=O)NC3=O)cc2S(=O)(=O)F)CC1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 18/20 0.45
▸ DDB1 Q16531 14/20 0.45
▸ IKZF2 Q9UKS7 1/20 0.36
▸ DRD2 P14416 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443893 0.89 CRBN (0.43) CRBNDDB1DRD2
SCHEMBL31443705 0.88 CRBN (0.43) CRBNDDB1IKZF2DRD2
SCHEMBL25271013 0.87 CRBN (0.47) CRBNDDB1IKZF2
SCHEMBL31443812 0.84 DDB1 (0.48) CRBNDDB1IKZF2DRD2
SCHEMBL31443791 0.83 CRBN (0.46) CRBNDDB1
SCHEMBL31444151 0.82 DDB1 (0.48) CRBNDDB1
SCHEMBL31444182 0.81 CRBN (0.52) CRBNDDB1
SCHEMBL31323750 0.81 DDB1 (0.53) CRBNDDB1IKZF2DRD2
SCHEMBL25175404 0.81 DDB1 (0.53) CRBNDDB1IKZF2DRD2
SCHEMBL24124617 0.80 DDB1 (0.54) CRBNDDB1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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