SCHEMBL31443893

SCHEMBL31443893

CC(C)(C)OC(=O)CN1CCC(c2ccc(OC3CCC(=O)NC3=O)cc2S(=O)(=O)F)CC1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 17/20 0.43
▸ DDB1 Q16531 16/20 0.43
▸ CDK9 P50750 1/20 0.36
▸ WNT1 P04628 1/20 0.36
▸ GSK3B P49841 1/20 0.36
▸ DYRK1A Q13627 1/20 0.36
▸ DRD2 P14416 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443815 0.90 CRBN (0.42) CRBNDDB1
SCHEMBL31443772 0.89 CRBN (0.45) CRBNDDB1DRD2
SCHEMBL31444151 0.87 DDB1 (0.48) CRBNDDB1
SCHEMBL31443833 0.87 DDB1 (0.44) CRBNDDB1DRD2
SCHEMBL25168320 0.83 DDB1 (0.52) CRBNDDB1
SCHEMBL25173024 0.83 DDB1 (0.52) CRBNDDB1
SCHEMBL23301396 0.83 DDB1 (0.52) CRBNDDB1
SCHEMBL25169522 0.81 CRBN (0.42) CRBNDDB1CDK9
SCHEMBL28947554 0.79 DDB1 (0.45) CRBNDDB1CDK9WNT1GSK3B
SCHEMBL29943279 0.79 DDB1 (0.45) CRBNDDB1CDK9WNT1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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