Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443896 | 0.83 | ELANE (0.35) | PDE4APDE4BPDE4CPDE4DELANE | |
| SCHEMBL31443866 | 0.79 | CHEK1 (0.33) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL31444148 | 0.78 | ELANE (0.30) | ELANE | |
| SCHEMBL17895516 | 0.70 | PARP1 (0.41) | METAP2 | |
| SCHEMBL29484266 | 0.70 | PARP1 (0.41) | METAP2 | |
| SCHEMBL5262100 | 0.70 | HAO1 (0.43) | METAP2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31444033 | 0.68 | ELANE (0.39) | ELANELMNAHPGDTSHRMAPK1 | |
| SCHEMBL16911720 | 0.68 | MAPT (0.54) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL29033968 | 0.68 | MAPT (0.41) | METAP2CYP1A2TSHRMAPK1CYP2C19 | |
| SCHEMBL27916599 | 0.67 | HDAC3 (0.43) | METAP2LMNATP53HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096856-A1 | COVALENT CEREBLON LIGANDS | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |