Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27858187 | 0.86 | MAPT (0.44) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL29033980 | 0.82 | MAPT (0.52) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL27844926 | 0.81 | MAPT (0.48) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL27825929 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL27680977 | 0.79 | MEN1 (0.45) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL20630984 | 0.77 | CHEK1 (0.49) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8782300 | 0.75 | MAPT (0.41) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL28242342 | 0.75 | AR (0.46) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL3014712 | 0.74 | MAPT (0.49) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL25377636 | 0.73 | S100A4 (0.42) | MAPTMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444436-A | Synthesis method of aminophenylpyrazole compound | 曲靖师范学院 | 2023-07-18 | — | — | CN | disclosed |