SCHEMBL31443891

SCHEMBL31443891

CC(C)(C)OC(=O)CN1CCC(c2ccc(NC3CCC(=O)NC3=O)cc2OS(C)(=O)=O)CC1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 18/20 0.46
▸ CRBN Q96SW2 18/20 0.46
▸ HDAC8 Q9BY41 2/20 0.42
▸ HDAC3 O15379 1/20 0.38
▸ HDAC1 Q13547 1/20 0.38
▸ HDAC2 Q92769 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443858 0.89 DDB1 (0.46) DDB1CRBNHDAC8HDAC3HDAC1
SCHEMBL23551339 0.87 DDB1 (0.49) DDB1CRBNHDAC8HDAC3HDAC1
SCHEMBL30120231 0.86 CRBN (0.49) DDB1CRBNHDAC8HDAC3HDAC1
SCHEMBL23551319 0.86 CRBN (0.49) DDB1CRBNHDAC8HDAC3HDAC1
SCHEMBL23540366 0.86 CRBN (0.49) DDB1CRBNHDAC8HDAC3HDAC1
SCHEMBL29535371 0.86 CRBN (0.49) DDB1CRBNHDAC8HDAC3HDAC1
SCHEMBL23551320 0.86 CRBN (0.49) DDB1CRBNHDAC8HDAC3HDAC1
SCHEMBL30120249 0.86 CRBN (0.49) DDB1CRBNHDAC8HDAC3HDAC1
SCHEMBL31444198 0.85 CRBN (0.47) DDB1CRBNHDAC8
SCHEMBL23551736 0.84 DDB1 (0.47) DDB1CRBNHDAC8HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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