Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.47 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443818 | 0.93 | CRBN (0.47) | CRBNDDB1IKZF1HDAC8 | |
| SCHEMBL31443695 | 0.89 | CRBN (0.41) | CRBNDDB1IKZF1POLB | |
| SCHEMBL31443761 | 0.87 | DDB1 (0.58) | CRBNDDB1 | |
| SCHEMBL25451460 | 0.86 | CRBN (0.52) | CRBNDDB1IKZF1HDAC8POLB | |
| SCHEMBL29877207 | 0.85 | CRBN (0.51) | CRBNDDB1IKZF1HDAC8POLB | |
| SCHEMBL24125789 | 0.85 | CRBN (0.51) | CRBNDDB1IKZF1HDAC8POLB | |
| SCHEMBL31443833 | 0.85 | DDB1 (0.44) | CRBNDDB1 | |
| SCHEMBL31443891 | 0.85 | DDB1 (0.46) | CRBNDDB1HDAC8 | |
| SCHEMBL24819375 | 0.83 | CRBN (0.53) | CRBNDDB1IKZF1HDAC8POLB | |
| SCHEMBL31443969 | 0.82 | DDB1 (0.45) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096856-A1 | COVALENT CEREBLON LIGANDS | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |