SCHEMBL31444018

SCHEMBL31444018

CC(C)(C)OC(=O)N1CCN(c2ccc(C3CCC(=O)NC3=O)cc2OS(=O)(=O)F)CC1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 15/20 0.58
▸ CRBN Q96SW2 15/20 0.58
▸ BACE1 P56817 3/20 0.39
▸ HRH3 Q9Y5N1 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444160 0.88 DDB1 (0.61) DDB1CRBNBACE1HRH3
SCHEMBL30955788 0.88 DDB1 (0.63) DDB1CRBNBACE1
SCHEMBL26641335 0.86 DDB1 (0.66) DDB1CRBNBACE1
SCHEMBL29197146 0.85 DDB1 (0.64) DDB1CRBNBACE1HRH3
SCHEMBL27225148 0.84 DDB1 (0.66) DDB1CRBNBACE1
SCHEMBL31444146 0.84 DDB1 (0.66) DDB1CRBNBACE1
SCHEMBL31443569 0.82 CRBN (0.45) DDB1CRBN
SCHEMBL31443879 0.82 CRBN (0.40) DDB1CRBN
SCHEMBL23301226 0.80 DDB1 (0.67) DDB1CRBN
SCHEMBL21876964 0.80 DDB1 (0.67) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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