SCHEMBL31443879

SCHEMBL31443879

O=C(O)CN1CCN(c2ccc(C3CCC(=O)NC3=O)cc2OS(=O)(=O)F)CC1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 18/20 0.40
▸ DDB1 Q16531 15/20 0.40
▸ GSPT1 P15170 1/20 0.36
▸ IKZF3 Q9UKT9 3/20 0.35
▸ POLB P06746 1/20 0.35
▸ DRD2 P14416 1/20 0.34
▸ DRD4 P21917 1/20 0.34
▸ DRD3 P35462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444014 0.85 CRBN (0.40) CRBNDDB1GSPT1
SCHEMBL27452177 0.84 CRBN (0.42) CRBNDDB1IKZF3DRD2
SCHEMBL30796306 0.84 CRBN (0.42) CRBNDDB1IKZF3DRD2
SCHEMBL30797044 0.84 CRBN (0.42) CRBNDDB1IKZF3DRD2
SCHEMBL27452178 0.84 CRBN (0.42) CRBNDDB1IKZF3DRD2
SCHEMBL24753627 0.84 CRBN (0.42) CRBNDDB1IKZF3DRD2
SCHEMBL31443569 0.84 CRBN (0.45) CRBNDDB1GSPT1POLB
SCHEMBL31444018 0.82 DDB1 (0.58) CRBNDDB1
SCHEMBL31443950 0.79 DDB1 (0.39) CRBNDDB1DRD2DRD4DRD3
SCHEMBL30955758 0.77 CRBN (0.51) CRBNDDB1GSPT1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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