SCHEMBL31444063

SCHEMBL31444063

CC(C)(C)OC(=O)N1CCC(c2ccc(N3CCC(=O)NC3=O)cc2O)CC1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ THRB P10828 1/20 0.47
▸ DDB1 Q16531 12/20 0.46
▸ CRBN Q96SW2 12/20 0.46
▸ GPR119 Q8TDV5 7/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443716 0.87 GPR119 (0.45) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL26684271 0.85 SCN9A (0.56) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL30087031 0.85 DDB1 (0.52) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL22119581 0.85 DDB1 (0.52) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL22119552 0.84 DDB1 (0.57) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL31444055 0.84 DDB1 (0.44) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL26849701 0.83 SCN9A (0.46) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL25338243 0.82 USP30 (0.45) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL26683778 0.82 SCN9A (0.44) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL25337552 0.81 KDM4E (0.49) KDM4EMAPTTHRBDDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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