SCHEMBL31444112

SCHEMBL31444112

CS(=O)(=O)Oc1cc(C2CCC(=O)NC2=O)ccc1C1CCNCC1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 13/20 0.47
▸ DDB1 Q16531 12/20 0.47
▸ POLB P06746 1/20 0.43
▸ HTR6 P50406 6/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444037 0.89 CRBN (0.46) CRBNDDB1POLBHTR6
SCHEMBL31443868 0.89 CRBN (0.46) CRBNDDB1POLBHTR6
SCHEMBL31443695 0.81 CRBN (0.41) CRBNDDB1POLB
SCHEMBL31444170 0.81 DDB1 (0.50) CRBNDDB1
SCHEMBL31443983 0.81 DDB1 (0.55) CRBNDDB1HTR6
SCHEMBL31443761 0.80 DDB1 (0.58) CRBNDDB1
SCHEMBL31444189 0.79 CRBN (0.49) CRBNDDB1POLBHTR6
SCHEMBL31444198 0.78 CRBN (0.47) CRBNDDB1POLB
SCHEMBL24124611 0.78 CRBN (0.53) CRBNDDB1POLB
SCHEMBL29977325 0.78 CRBN (0.53) CRBNDDB1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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