SCHEMBL31444129

SCHEMBL31444129

O=C1CCC(Oc2cccc(SCc3ccccc3)c2)C(=O)N1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.62
DDB1 Q16531 16/20 0.62
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443952 0.86 CRBN (0.55) CRBNDDB1
SCHEMBL31443619 0.86 CRBN (0.55) CRBNDDB1MAOAMAOB
SCHEMBL31444207 0.82 CRBN (0.54) CRBNDDB1
SCHEMBL31443873 0.81 CRBN (0.56) CRBNDDB1
SCHEMBL31443626 0.80 CRBN (0.67) CRBNDDB1MAOAMAOB
SCHEMBL31444109 0.79 CRBN (0.51) CRBNDDB1
SCHEMBL21965432 0.78 CRBN (1.00) CRBNDDB1
SCHEMBL31443826 0.74 CRBN (0.68) CRBNDDB1
SCHEMBL31444155 0.74 CRBN (0.68) CRBNDDB1
SCHEMBL31444175 0.74 DDB1 (0.68) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed