Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESRRA | P11474 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443988 | 0.88 | BACE1 (0.52) | BACE1STSRBP4ESRRBESR1 | |
| SCHEMBL34465976 | 0.85 | BACE1 (0.59) | BACE1STSRBP4LMNAALDH1A1 | |
| SCHEMBL14852526 | 0.85 | BACE1 (0.59) | BACE1STSRBP4LMNAALDH1A1 | |
| SCHEMBL15775206 | 0.82 | BACE1 (0.55) | BACE1RBP4ESRRBESR1ESRRA | |
| SCHEMBL30376322 | 0.82 | BACE1 (0.55) | BACE1RBP4ESRRBESR1ESRRA | |
| SCHEMBL7123953 | 0.81 | BACE1 (0.54) | BACE1RBP4LMNAALDH1A1MAPT | |
| SCHEMBL630905 | 0.81 | RBP4 (0.66) | BACE1RBP4ESRRBESR1ESRRA | |
| SCHEMBL31443998 | 0.81 | BACE1 (0.57) | BACE1STSRBP4ESRRBESR1 | |
| SCHEMBL6628496 | 0.81 | BACE1 (0.54) | BACE1RBP4ESRRBESR1ESRRA | |
| SCHEMBL31443728 | 0.81 | BACE1 (0.54) | BACE1RBP4ESRRBESR1ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096856-A1 | COVALENT CEREBLON LIGANDS | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |