SCHEMBL31444179

SCHEMBL31444179

COCOc1cccc2c(CC(=O)O)noc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.67
MAPT P10636 4/20 0.43
AKR1B1 P15121 2/20 0.40
ACHE P22303 1/20 0.38
PTPN1 P18031 1/20 0.37
PPARG P37231 2/20 0.36
PPARD Q03181 2/20 0.36
PPARA Q07869 2/20 0.36
FFAR1 O14842 1/20 0.36
POLB P06746 3/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CHEK1 O14757 1/20 0.35
AURKA O14965 1/20 0.35
DAPK3 O43293 1/20 0.35
JAK2 O60674 1/20 0.35
ABL1 P00519 1/20 0.35
NTRK1 P04629 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443897 0.85 SMN1; SMN2 (0.51) SMN1; SMN2MAPTPTPN1FFAR1POLB
SCHEMBL17748268 0.80 SMN1; SMN2 (1.00) SMN1; SMN2MAPTAKR1B1FFAR1POLB
SCHEMBL31444048 0.77 SMN1; SMN2 (0.53) SMN1; SMN2MAPTAKR1B1PTPN1PPARG
SCHEMBL24754426 0.75 SMN1; SMN2 (0.68) SMN1; SMN2MAPTAKR1B1POLBKDM4E
SCHEMBL1614082 0.73 SMN1; SMN2 (0.55) SMN1; SMN2MAPTAKR1B1POLBKDM4E
SCHEMBL16256130 0.71 SMN1; SMN2 (0.72) SMN1; SMN2MAPTFFAR1KDM4EHPGD
SCHEMBL11843479 0.71 SMN1; SMN2 (0.62) SMN1; SMN2MAPTAKR1B1POLBKDM4E
SCHEMBL1884182 0.69 L3MBTL1 (0.57) SMN1; SMN2AKR1B1PPARGPOLBTDP1
SCHEMBL29874929 0.69 L3MBTL1 (0.57) SMN1; SMN2AKR1B1PPARGPOLBTDP1
Methyl Alcohol SCHEMBL11211940 0.68 MAPT (0.63) SMN1; SMN2MAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed